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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
7 DPC

18 matching records from 18 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
T  brachyury, T-box transcription factor T   (Synonyms: Bra, T1, Tbxt)
Results  Reference
1J:238298 Acampora D, Omodei D, Petrosino G, Garofalo A, Savarese M, Nigro V, Di Giovannantonio LG, Mercadante V, Simeone A, Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast. Cell Rep. 2016 Jun 21;15(12):2651-64
1J:146503 Downs KM, Inman KE, Jin DX, Enders AC, The Allantoic Core Domain: New insights into development of the murine allantois and its relation to the primitive streak. Dev Dyn. 2009 Mar;238(3):532-53
1J:329267 Drozd AM, Mariani L, Guo X, Goitea V, Menezes NA, Ferretti E, Progesterone Receptor Modulates Extraembryonic Mesoderm and Cardiac Progenitor Specification during Mouse Gastrulation. Int J Mol Sci. 2022 Sep 7;23(18)
1J:142039 Egea J, Erlacher C, Montanez E, Burtscher I, Yamagishi S, Hess M, Hampel F, Sanchez R, Rodriguez-Manzaneque MT, Bosl MR, Fassler R, Lickert H, Klein R, Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation. Genes Dev. 2008 Dec 1;22(23):3349-3362
1J:279070 Hernandez-Martinez R, Ramkumar N, Anderson KV, p120-catenin regulates WNT signaling and EMT in the mouse embryo. Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16872-16881
1J:195125 Hoffman JA, Wu CI, Merrill BJ, Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification. Development. 2013 Apr;140(8):1665-75
1J:254969 Huang X, Balmer S, Yang F, Fidalgo M, Li D, Guallar D, Hadjantonakis AK, Wang J, Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling. Elife. 2017 Nov 23;6:e33333
1*J:112218 Inman KE, Downs KM, Localization of Brachyury (T) in embryonic and extraembryonic tissues during mouse gastrulation. Gene Expr Patterns. 2006 Dec;6(8):783-93
1J:217820 Larabee SM, Coia H, Jones S, Cheung E, Gallicano GI, miRNA-17 Members that Target Bmpr2 Influence Signaling Mechanisms Important for Embryonic Stem Cell Differentiation In Vitro and Gastrulation in Embryos. Stem Cells Dev. 2015 Feb 1;24(3):354-71
1J:176115 Lu H, Huang YY, Mehrotra S, Droz-Rosario R, Liu J, Bhaumik M, White E, Shen Z, Essential Roles of BCCIP in Mouse Embryonic Development and Structural Stability of Chromosomes. PLoS Genet. 2011 Sep;7(9):e1002291
1J:258132 Morgani SM, Metzger JJ, Nichols J, Siggia ED, Hadjantonakis AK, Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning. Elife. 2018 Feb 7;7:e32839
1*J:264612 Morgani SM, Saiz N, Garg V, Raina D, Simon CS, Kang M, Arias AM, Nichols J, Schroter C, Hadjantonakis AK, A Sprouty4 reporter to monitor FGF/ERK signaling activity in ESCs and mice. Dev Biol. 2018 Sep 1;441(1):104-126
1J:264114 Mulas C, Chia G, Jones KA, Hodgson AC, Stirparo GG, Nichols J, Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo. Development. 2018 Jun 18;145(12):dev159103
1*J:276571 Rajderkar S, Mann JM, Panaretos C, Yumoto K, Li HD, Mishina Y, Ralston B, Kaartinen V, Trim33 is required for appropriate development of pre-cardiogenic mesoderm. Dev Biol. 2019 Jun 15;450(2):101-114
1*J:242135 Rodriguez AM, Jin DX, Wolfe AD, Mikedis MM, Wierenga L, Hashmi MP, Viebahn C, Downs KM, Brachyury drives formation of a distinct vascular branchpoint critical for fetal-placental arterial union in the mouse gastrula. Dev Biol. 2017 May 15;425(2):208-222
1J:307834 Scheibner K, Schirge S, Burtscher I, Buttner M, Sterr M, Yang D, Bottcher A, Ansarullah, Irmler M, Beckers J, Cernilogar FM, Schotta G, Theis FJ, Lickert H, Epithelial cell plasticity drives endoderm formation during gastrulation. Nat Cell Biol. 2021 Jul;23(7):692-703
1J:282925 Tosic J, Kim GJ, Pavlovic M, Schroder CM, Mersiowsky SL, Barg M, Hofherr A, Probst S, Kottgen M, Hein L, Arnold SJ, Eomes and Brachyury control pluripotency exit and germ-layer segregation by changing the chromatin state. Nat Cell Biol. 2019 Dec;21(12):1518-1531
1*J:242062 Wolfe AD, Rodriguez AM, Downs KM, STELLA collaborates in distinct mesendodermal cell subpopulations at the fetal-placental interface in the mouse gastrula. Dev Biol. 2017 May 01;425(1):44-57

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory